主持或参加科研项目
1、 湖南省自然科学面上项目，基于铁死亡的肾小管上皮细胞释放 促纤维化因子探究METTL3/lncRNA XIST介导肾纤维化的机制，2023/01-2025/12，5万元，在研，主持
2、长沙市自然科学基金项目，kq2208379，自体材料修复技术在腹腔镜上尿路重建手术中的应用创新及推广，2023/01-2025/12，5万元，在研，主持
3、湖南省自然科学面上项目，2020JJ4870，FAK/PI3K/Akt/mTOR通路介导细胞自噬在梗阻性肾病肾间质纤维化中的作用与机制研究，2020/01-2022/12，5万元，已结题，主持
4、湖南省自然科学青年基金，2015JJ3162，肾癌中ZEB2调控相关miRNAs的鉴定及其抑制肿瘤转移机制的研究，2015/01-2017/12，4万元，已结题，主持
5、国家自然科学基金面上项目，81770693，整合素β1/FAK促进梗阻性肾病肾间质纤维化过程的机制研究，2018/01-2021/12，55万元，在研，参加（排名第3)
6、国家自然科学基金面上项目，81570627，CaMKⅡ介导的Smad2/3磷酸化在尿道瘢痕形成中的作用及机制研究，2016/01-2018/12，56万元，已结题，参加（排名第3)
7、湖南省自然科学基金面上项目，2015JJ2152，FOXM1与雄激素受体协同调节CD6基因转录和前列腺癌发展的机理，2015/01-2017/12，4万元，在研，参加（排名第2)
以第一或通讯作者（含并列）发表的论文
1、Weiping Xia, Xiang Chen , Bingsheng Li , Hequn Chen , Zewu Zhu, Yao He, Yu Gan, Bo Zhang , Kangning Wang , Yang Li , Zexiang Jiang , Jin Long , Zhi Chen , Transabdominal Laparoscopic Ureteroureterostomy With the Intraoperative Retrograde Ureteroscopy-Assisted Technique for Multiple Ureteral Polyps: A Single-Center 10 Years Experiences ，Front Surg. 2022 Feb 25;9:814290.
2、B. Zhang, F. Ru, X. Chen, Z. Chen, Autophagy attenuates renal fibrosis in obstructive nephropathy through inhibiting epithelial-to-mesenchymal transition, Zhong Nan Da Xue Xue Bao Yi Xue Ban 46(6) (2021) 601-608.
3、B. Zhang, X. Chen, F. Ru, Y. Gan, B. Li, W. Xia, G. Dai, Y. He, Z. Chen（并列通讯）, Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis, Cell Death Dis 12(9) (2021) 843.
4、R.Z. Xue, Z.Y. Tang, M.Q. Zeng, L. Huang, J.J. Chen, Z. Chen, Two-stage laparoscopic repair of two-level ureteral strictures: our experience of 8 patients, Urol J (2018).
5、W.P. Xia, X. Chen, F. Ru, Y. He, P.H. Liu, Y. Gan, B. Zhang, Y. Li, G.Y. Dai, Z.X. Jiang, Z. Chen, Knockdown of lncRNA XIST inhibited apoptosis and inflammation in renal fibrosis via microRNA-19b-mediated downregulation of SOX6, Mol Immunol 139 (2021) 87-96.
6、W. Xia, Y. He, Y. Gan, B. Zhang, G. Dai, F. Ru, Z. Jiang, Z. Chen（并列通讯）, X. Chen, Long Non-coding RNA: An Emerging Contributor and Potential Therapeutic Target in Renal Fibrosis, Front Genet 12 (2021) 682904.
7、W. Xia, X. Chen, L. Liu, Z. Chen（并列通讯）, F. Ru, Comparison of modified hand-assisted retroperitoneoscopic laparoscopic nephrectomy and open nephrectomy in patients with benign inflammatory non-functioning kidney diseases, Transl Androl Urol 10(5) (2021) 2027-2034.
8、Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis, Chunliang Cheng; Dongxu Qiu; Jinbo Chen; Xiongbing Zu; Jinhui Liu; Huihuang Li; Jiao Hu; Zhenglin Yi; Tongchen He; Zhi Chen（并列通讯）; Yu Cui. Front Pharmacol, 2021, 12(707271).
9、Z.Y. Tang, Z. Chen（并列第一）, Y. He, X. Chen, X.L. Fang, D.J. Li, L. Huang, Laparoendoscopic single-site ureteroureterostomy with intraoperative retrograde ureteroscopy-assisted technique for benign proximal and middle ureteral strictures: a single-center experience, J Laparoendosc Adv Surg Tech A 24(7) (2014) 493-6.
10、M. Mo, M. Zhou, L. Wang, L. Qi, K. Zhou, L.F. Liu, Z. Chen（并列通讯）, X.B. Zu, CCL21/CCR7 enhances the proliferation, migration, and invasion of human bladder cancer T24 cells, PLoS One 10(3) (2015) e0119506.
11、Y. Li, P. Chen, Z. Chen, A population-based study to predict distant metastasis in patients with renal cell carcinoma, Ann Palliat Med 10(4) (2021) 4273-4288.
12、Y. He, Z. Chen（并列第一）, X.L. Fang, Y.C. Luo, P.Y. Dai, M.L. Lu, X. Chen, Transumbilical laparoendoscopic single-site decortication of peripelvic renal cyst: a case report, Urol J 11(3) (2014) 1699-701.
13、 Z. Chen, P. Zhou, Z.Q. Yang, Y. Li, Y.C. Luo, Y. He, N.N. Li, C.Q. Xie, C. Lai, X.L. Fang, X. Chen, Transperitoneal mini-laparoscopic pyeloplasty and concomitant ureteroscopy-assisted pyelolithotomy for ureteropelvic junction obstruction complicated by renal caliceal stones, PLoS One 8(1) (2013) e55026.
14、Z. Chen, Z.Y. Tang, H.T. Liu, X. Chen, Treatment of juxtaglomerular cell tumor of the kidney by retroperitoneal laparoscopic partial nephrectomy, Urol J 10(4) (2014) 1160-1.
15、Z. Chen, Z.Y. Tang, Y. He, L.F. Liu, D.J. Li, X. Chen, miRNA-205 is a candidate tumor suppressor that targets ZEB2 in renal cell carcinoma, Oncol Res Treat 37(11) (2014) 658-64.
16、Z. Chen, Z.Y. Tang, B.Y. Fan, X. Chen, P. Zhou, Y.C. Luo, Y. He, C.Q. Xie, C. Lai, X.L. Fang, Retroperitoneoscopic upper pole nephroureterectomy in duplex kidney: focus on the role of dilated upper pole ureter, Urol J 10(4) (2014) 1046-53.
17、Z. Chen, Y. He, Z.Y. Tang, W. He, X. Chen, Laparoscopic ureteroureterostomy with the intraoperative retrograde ureteroscopy-assisted technique for inverted-Y ureteral duplication with a blind-ending branch, Urol Int 94(2) (2015) 163-5.
18、Z. Chen, X. Chen, Z.H. Wu, Y.C. Luo, N.N. Li, Treatment of retrocaval ureter by retroperitoneal laparoscopic ureteroureterostomy: experience on 12 patients, J Laparoendosc Adv Surg Tech A 21(9) (2011) 803-7.
19、Z. Chen, X. Chen, Z.H. Wu, Y.C. Luo, Y. He, N.N. Li, C.Q. Xie, C. Lai, Feasibility and safety of retroperitoneal laparoendoscopic single-site dismembered pyeloplasty: a clinical report of 10 cases, J Laparoendosc Adv Surg Tech A 22(7) (2012) 685-90.
20、Z. Chen, X. Chen, Y.C. Luo, Y. He, N.N. Li, C.Q. Xie, C. Lai, X.L. Fang, Retroperitoneal laparoendoscopic single-site ureterolithotomy and ureteroureterostomy for retrocaval ureter with ureteral calculus: first case report, Scand J Urol Nephrol 46(6) (2012) 437-40.
21、Z. Chen, X. Chen, Y.C. Luo, Y. He, N.N. Li, C.Q. Xie, C. Lai, Retroperitoneal laparoendoscopic single-site simple nephrectomy: initial experience, J Endourol 26(6) (2012) 647-51.
22、Z. Chen, X. Chen, Y.C. Luo, Y. He, N.N. Li, Z.H. Wu, Retroperitoneoscopic decortication of symptomatic peripelvic renal cysts: Chinese experience, Urology 78(4) (2011) 803-7.
23、Z. Chen, X. Chen, Y.C. Luo, Technical modifications of double-J stenting for retroperitoneal laparoscopic dismembered pyeloplasty in children under 5 years old, PLoS One 6(8) (2011) e23073.
24、刘建， 巩昱辰，张波，甘宇，李冰晟，何垚，陈志，3D可视化技术在腹腔镜下肾错构瘤剜除术中的应用，中国内镜杂志, 2021, 27(06): 57-61.
25、黄卫，朱礼乐，汝峰，陈湘，陈志，远端尿道黏膜环切断在经尿道钬激光前列腺剜除手术治疗良性前列腺增生中的应用，中国内镜杂志, 2021, 27(07): 31-35.
26、陈志，杨中青，齐琳，何垚，罗延诚，李南南，谢超群，赖晨， 方小龙，陈湘，经脐单孔腹腔镜下离断性肾盂成形术治疗肾盂输尿管连接处梗阻的可行性和安全性分析，中华泌尿外科杂志, 2014, 35(7): 535-538
27、陈志，唐正严，丁见，陈湘，李东杰，罗宽，黄亮，齐琳，逆行或顺行球囊扩张术治疗输尿管狭窄，中国内镜杂志, 2014, (04): 385-387
28、陈志，陈湘，罗延诚，何垚，李南南，谢超群，赖晨，单孔后腹腔镜下单纯性肾切除术的初步体会，中国内镜杂志, 2012, (01): 48-51
29、陈志，陈湘，谢晋良，周成，改良手助后腹腔镜下活体供肾切取术85例中国内镜杂志, 2011, (04): 370-373
30、陈志, 陈湘, 齐琳 , 陈亮, 罗延诚, 何垚， 李南南， 谢超群，后腹腔镜下离断式肾盂成形术 治疗 小儿肾盂输尿管连接部梗阻 85 例报告中南大学学报 (医学版 )， 2011,36 (5)
31、陈志，王桂林，陈湘，齐琳，唐正严，何垚，微型腹腔镜下肾盂成形术联合输尿管镜辅助肾盂切开取石术治疗肾盂输尿管连接部梗阻合并肾结石，中国内镜杂志，2015，21（6）：663-665
获奖
1、泌尿外科腹腔镜手术系列新技术，湖南省人民政府，湖南省科技进步奖，二等奖，2015，排名第二
2、泌尿外科腹腔镜手术系列新技术，湖南医学科技奖奖励委员会，第十二届湖南医学科技奖，二等奖，2015，排名第二
3、3D可视化技术在嗜铬细胞瘤/副神经节瘤腹腔镜手术中的应用
中南大学临床研究与医疗新技术成果奖二等奖, 2018，排名第
二
4、 国际首创双镜联合修复输尿管狭窄或损伤技术，中南大学临床研究与医疗新技术成果奖二等奖, 2018，排名第二
5、自主创新双镜联合及单孔腹腔镜技术治疗复杂泌尿系上尿路疾病，第十五届湖南医学科技奖，三等奖，2018，排名第三
