主持课题:
2022年-2024年主持承担中日友好医院高水平医院专项临床研究项目-《腹腔镜下卵巢肿瘤无瘤防御性穿刺抽吸和剔除术的临床研究》。
参与课题:
1.首都卫生发展科研专项项目,膀腹腔镜下卵巢畸胎瘤剔除术中预防肿瘤内容物泄漏方法的临床研究。
2.中国健康促进基金会,Inhibin调控代谢的分子机制及其工程化控释颗粒细胞微囊治疗效果评价。
3.生殖健康及重大出生缺陷防控研究”专项“生殖疾病防治规范化体系建立”项目,卵巢功能异常导致生育力降低相关疾病分级诊疗体系建立及示范研究。
4.2022年北京协和医院中央高水平医院临床科研专项项目,“活体病理”双光子宫颈显微成像系统的研发及在宫颈病变的应用推广。
5.国家自然科学基金,Piwil2通过PDK1介导代谢重编程调控子宫颈上皮内瘤变转归方向的机制研究。
发表论文:
Wenhui Wang , Xiaoning Bi , Ye Feng , Xue Ming , Guo Saina , Wang Kun , Bin Ling , Huan Yu*. Efficacy and Safety of Immune Checkpoint Inhibitors on Advanced Cervical Cancer: A Systematic Review and Meta-analysis. J Immunother 2024 Dec 5.
Wang W, Hou S, Wang K, Ling B and Yu Huan* (2024) Association of body roundness index with female infertility: 2013–2018 NHANES. Front. Nutr. 30 October 2024.
Wenhui Wang, Shengdi Hou, Kun Wang, HUAN YU* and Bin Ling*. Dietary Inflammatory Index and female infertility: findings from NHANES survey. Front. Nutr., 19 September 2024.Sec. Clinical Nutrition.Volume 11 - 2024.
Hirono Takae, Feng Ye, Wang Wenhui, Yu, Huan*.Spontaneous recurrent menstrual pneumothorax: a case report.Annals of Medicine & Surgery. 2023,December 6 .
Yu Huan,Liang Jing,Liang Haiyan, et al. Laparoscopically assisted ovarian cystectomy with totally enclosed protective device for tumor isolation [J].Int J Gynaecol Obstet. 2023 Feb;160(2):588-593. Epub 2022 Oct 8.
Yu Huan,Ma Li,Bian Meilu, et al. Association of abnormal vaginal microflora and HPV infection in cervical precancerous lesions: a retrospective study [J].JOURNAL OF INFECTION IN DEVELOPING COUNTRIES,2022,16(6):1089-1095.
凌斌,于欢, 等. 子宫腹壁悬吊术的临床应用 [J].中国实用妇科与产科杂志,2021,37(12):1181-1183.
Yu Huan,Wang Wenhui,Liang Haiyan, et al. Severe Adverse Toxic Effects of Low-Dose Methotrexate Treatment on an Ectopic Pregnancy Patient With Methylenetetrahydrofolate Reductase Mutations: A Case Report [J].FRONTIERS IN MEDICINE,2021,8.
Yu Huan,Yang Zi,Ding Xiaoyan, et al. Effects of serum from patients with early-onset pre-eclampsia, HELLP syndrome, and antiphospholipid syndrome on fatty acid oxidation in trophoblast cells [J].ARCHIVES OF GYNECOLOGY AND OBSTETRICS,2015,292(3):559-567.
Yu Huan,Yang Zi,Ding Xiaoyan, et al. Correlation between the different chain lengths of free fatty acid oxidation and ability of trophoblastic invasion [J].CHINESE MEDICAL JOURNAL,2014,127(19):3378-3382.
参编著作
1、《威廉姆斯产科学》 第25版 主译 杨慧霞 漆红波 郑勤田 人民卫生出版社 2020年第一版
2、《威廉姆斯妇科学》 第3版 主译 段华 王建六 北京大学医学出版社 2021年第一版
3、《微创无瘤防御理论与实践》 主编 凌斌 高等教育出版社 2022年第一版