科研上,目前承担国家自然基金项目级多项市级以上科研课题,内容涉及妇科肿瘤的发病机理,肿瘤化疗的耐药机制及肿瘤治疗的新方法等。在国内外杂志发表论文100余篇,主编、参编专著十余部。
发表论文:
(1) Cao C, Lu S, Sowa A, Kivlin R, Amaral A, Chu W, Yang H, Di W, Wan Y.Priming with EGFR tyrosine kinase inhibitor and EGF sensitizes ovarian cancer cells to respond to chemotherapeutical drugs.Cancer Letters.2008,266: 249–262.
(2) Ji C, Cao C, Lu S, Kivlin R, Amaral A, Kouttab N, Yang H, Chu W, Bi Z, Di W, Wan Y.Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells.Cancer Chemother Pharmacol.2008 Oct;62(5):857-65.
(3) Di W, Guo SW. The search for genetic variants predisposing women to endometriosis.Curr Opin Obstet Gynecol. 2007 Aug;19(4):395-401. Review.
(4) Related Articles, LinksQiu L, Zhou C, Sun Y, Di W, Scheffler E, Healey S, Kouttab N, Chu W, Wan Y.Crosstalk between EGFR and TrkB enhances ovarian cancer cell migration and proliferation.Int J Oncol. 2006 Oct;29(4):1003-11.
(5) Qiu L, Zhou C, Sun Y, Di W, Scheffler E, Healey S, Wanebo H, Kouttab N, Chu W, Wan Y.Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells.Oncol Rep. 2006 Oct;16(4):907-13.
(6) Zhang S, Lin QD, DI W. Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1.Int J Gynecol Cancer. 2006 Mar-Apr;16(2):522-31.
(7) Qiu L, Di W, Jiang Q, Scheffler E, Derby S, Yang J, Kouttab N, Wanebo H, Yan B, Wan Y. Inhibition of EGFR/PI13/AKT cell survival pathway promotes TSA’s effect on cell death and migration in human ovarian cancer cells.Int J Oncol. 2006 Jul;29(1):269-78.
(8) Qiu L, Di W, Jiang Q, Scheffler E, Derby S, Yang J, Kouttab N, Wanebo H, Yan B, Wan Y.Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death.Int J Oncol. 2005 Nov;27(5):1441-8.
(9) Qiu L, Wang Q, Di W, Jiang Q, Schefeller E, Derby S, Wanebo H, Yan B, Wan Y.Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid.Int J Oncol. 2005 Sep;27(3):823-30.
(10) Wang X, Lin Q, Ma Z, Hong Y, Zhao A, Di W, Lu P.Association of the A/G polymorphism at position 49 in exon 1 of CTLA-4 with the susceptibility to unexplained recurrent spontaneous abortion in the Chinese population.Am J Reprod Immunol. 2005 Feb;53(2):100-5.
(11) Wang X, Huang Z, Di W, Lin Q. Comparison of D&C and hysterectomy pathologic findings in endometrial cancer patients.Arch Gynecol Obstet. 2005 Jul;272(2):136-41