俞旻皓

社会任职

上海市抗癌协会胃肠肿瘤腹腔镜专业委员会委员
中国医疗保健国际交流促进会腔镜内镜外科分会委员
上海市抗癌协会大肠癌专业委员会肠癌转移学组委员
中国医师协会肛肠医师分会肠外肠内营养专业学组委员
中国医学装备协会腔镜与微创技术分会委员（第一届）
中国研究型医院学会肠外肠内营养学专业委员会青年委员
《肿瘤医学》专刊第二届编委会青年编委会青年编委
中国NOSES联盟上海分会理事

获奖荣誉

2011年
仁济医院优秀住院医师
2017年
仁济医院优秀单篇图文微信奖
2018年
雅培医学营养精英挑战赛-全国冠军
扬帆远航-消化肿瘤精英论坛-十二强优胜团队
2019年
上海交通大学医学院附属仁济医院健康科普大赛三等奖
上海交通大学医学院“优秀青年人才培育计划”培训班优秀学员
中国IBD青年说-亚军（最佳风采奖）
全国结直肠肿瘤中青年医师-达医生演讲大赛-亚军
结直肠外科精英团队临床技能邀请赛优秀奖
CSCO-赛诺菲消化肿瘤精英论坛-全国扬帆声势比赛十二强
达医生-例达巅峰-全国演讲大赛总决赛胃肠专场-希望之星
大中华结直肠腔镜外科学院-达人赛江苏&上海赛区-二等奖
2020年
第十三届中国医师协会外科医师年会“规范典型病例”
第七届“上海市健康传播设计大赛——新媒体类”三等奖
上海交通大学医学院2020年医学专业课程思政设计竞赛-十佳思政素材
2021年
上海交通大学医学院医学生健康科普摇篮计划科普导师
上海交通大学医学院健康科普大赛二等奖-指导老师
上海交通大学医学院本科优秀临床综述奖-指导老师
上海交通大学医学院附属仁济医院教学先进个人

科研成果

发表论文：
1.第一作者
1)俞旻皓#,王正实,钟鸣.腹腔镜修补术在医源性结肠镜肠穿孔治疗中的应用体会(附7例报告)[J].腹腔镜外科杂志,2013,18(11):854-856.
2)俞旻皓#,彭友多,卞正乾,等. 溃疡性结肠炎36例手术治疗分析[J]. 中国临床医学, 2014(6) : 659-660.
3)俞旻皓#,钟鸣,叶光耀,等. 反穿刺技术在完全腹腔镜结直肠切除术中的应用[J]. 腹腔镜外科杂志,2014,19(7):497-500.
4)俞旻皓#,王正实,秦绍岚,等. 腹腔镜监控肠镜下(LMCP)息肉摘除术对比常规肠镜下息肉切除的随机对照临床研究[J]. 现代生物医学进展,2015,15(10):1858-1861.
5)俞旻皓#,祁洋,秦绍岚,等. 腹腔镜与开腹右半结肠癌全结肠系膜切除术的回顾性临床对照研究[J]. 外科理论与实践,2018,23(2):145-149.
6)郝秀秀#,俞旻皓*,钟鸣. 早期手术干预在小肠克罗恩病治疗中的价值[J]. 胃肠病学,2020,25(4):246-249.
7)俞旻皓#,WANG Q X;ZHANG R;XIAO W W.观察&等待策略与手术切除治疗新辅助放化疗后达到临床完全缓解的直肠癌患者疗效比较[J].结直肠肛门外科,2021,27(2):160-160.
8)Yu M#, Zhong M, Qiao Z*. Expression and clinical significance of cyclin kinase subunit 2 in colorectal cancer. Oncol Lett. 2013 Sep;6(3):777-780. (IF= 2.964)
9)Yu MH#, Luo Y#, Qin SL, Zhong M*. Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6974-80.
10)Yu MH#, Luo Y#, Qin SL, Wang ZS, Mu YF, Zhong M*. Up-regulated CKS2 promotes tumor progression and predicts a poor prognosis in human colorectal cancer. Am J Cancer Res. 2015 Aug 15;5(9):2708-18. (IF= 6.164)
11)Yu MH#, Zhang W*. TEAD1 enhances proliferation via activating SP1 in colorectal cancer. Biomed Pharmacother. 2016 Oct;83:496-501. (IF= 6.522)
12)Yu M#, Mu Y#, Qi Y#, Qin S, Qiu Y, Cui R, Zhong M*. Odontogenic ameloblast-associated protein (ODAM) inhibits human colorectal cancer growth by promoting PTEN elevation and inactivating PI3K/AKT signaling. Biomed Pharmacother. 2016 Dec;84:601-607. (IF= 6.523)
13)Yu M#, Luo Y#, Cong Z#, Mu Y, Qiu Y, Zhong M*. MicroRNA-590-5p Inhibits Intestinal Inflammation by Targeting YAP. J Crohns Colitis. 2018 Jul 30;12(8):993-1004. (IF=9.072)
14)Cui R#, Yu MH#, Chen JJ, Qin J, Yue B, Luo Y, Huang YZ, Zhou H, Zhong M*. Monopolar Electrosurgical Scissors Versus Harmonic Scalpel in Robotic Anterior Resection of Rectal Cancer: A Retrospective Cohort Study. J Laparoendosc Adv Surg Tech A. 2019 Jul;29(7):880-885. (IF= 1.874)
15)Yu M#, Cui R#, Huang Y#, Luo Y, Qin S, Zhong M*. Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway. EBioMedicine. 2019 Oct;48:264-276. (IF= 8.142)
16)Luo Y#, Yu MH#, Yan YR#, Zhou Y, Qin SL, Huang YZ, Qin J, Zhong M*. Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA-124-3p/STAT3/RelA signalling pathway in ulcerative colitis. J Cell Mol Med. 2020 Oct;24(19):11330-11342. (IF= 5.313)
17)Cui H#*, Yu W#, Yu M#, Luo Y, Yang M, Cong R, Chu X, Gao G*, Zhong M*. GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression. Cancer Sci. 2021 May;112(5):1798-1810. (IF= 6.710)
18)Luo Y#, Yu MH#, Huang YZ, Jing R, Qin J, Qin SL, Shah JN*, Zhong M*. Lymphadenectomy Around Inferior Mesenteric Artery in Low-Tie vs High-Tie Laparoscopic Anterior Resection: Short- and Long-Term Outcome of a Cohort of 614 Rectal Cancers. Cancer Manag Res. 2021 May 14;13:3963-3971. (IF=3.982)
2.通讯作者
1)Luo Y#, Ye GY#, Qin SL, Mu YF, Zhang L, Qi Y, Qiu YE, Yu MH*, Zhong M*. High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer. Int J Biochem Cell Biol. 2016 Jun;75:53-62. (IF= 5.080)
2)Wang ZS#, Zhong M#, Bian YH, Mu YF, Qin SL, Yu MH*, Qin J*. MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer. Oncotarget. 2016 Jul 12;7(28):44266-44276. (IF=4.141)
3)Luo Y#, Qiu YE#, Mu YF, Qin SL, Qi Y, Zhong M, Yu MH*, Ma LY*. Plastic wound protectors decreased surgical site infections following laparoscopic-assisted colectomy for colorectal cancer: A retrospective cohort study. Medicine (Baltimore). 2017 Sep;96(37):e7752. (IF= 1.882)
4)Cong Z#, Ye G#, Bian Z, Yu M*, Zhong M*. Jagged-1 attenuates LPS-induced apoptosis and ROS in rat intestinal epithelial cells. Int J Clin Exp Pathol. 2018 Aug 1;11(8):3994-4003.
5)Luo Y#, Chen JJ#, Lv Q#, Qin J, Huang YZ, Yu MH*, Zhong M*. Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling pathway. Cancer Lett. 2019 Jan;440-441:11-22. (IF= 8.674)
6)Cui R#, Yang L#, Wang Y#, Zhong M, Yu M*, Chen B*. Elevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation. Cancer Manag Res. 2020 Oct 19;12:10221-10228. (IF= 3.981)
7)Hao X#, Feng T, Yang Y, Shi Y, Jing R, Liu S, Luo Y, Qiao Y*, Zhong M*, Yu M*. Laparoscopic bowel resection combined with infliximab treatment (LaRIC) versus infliximab for terminal ileitis in Crohn's disease: a randomised, controlled, open-label trial. BMJ Open. 2020 Nov 16;10(11):e038429. (IF= 2.692)
8)Shi Y#, He W#, Zhong M*, Yu M*. MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases. Genomics. 2021 Jul;113(4):1988-1998. (IF= 5.731)
9)刘泽宇#,钟鸣,俞旻皓*. 腹腔镜镜头防雾防范的研究进展. 外科理论与实践[J].2021,26(5):463-465.
10)Zhang L, Yang L, Jiang S, Yu M. Nerve Dependence in Colorectal Cancer. Front Cell Dev Biol. 2022 Feb 10;10:766653. 
11)Liu S, Li L, Sun H, Chen B, Yu M*, Zhong M*. D3 Versus D2 Lymphadenectomy in Right Hemicolectomy: A Systematic Review and Meta-analysis. Surg Innov. 2022 Feb 1:15533506211060230.
3.参与发表的论文
1)叶光耀#,俞旻皓,钟鸣*. CKS2在结直肠癌中的表达和临床意义[J]. 胃肠病学,2013,18(3):159-162.
2)卞正乾#,钟鸣,俞旻皓,等. 经肛门内镜微创手术治疗直肠肿瘤（附74例报告）[J]. 外科理论与实践,2015(2):151-155.
3)骆洋#,卞正乾,叶光耀,俞旻皓,王正实,秦绍岚,慕逸飞,钟鸣*. 溶酶体相关4次跨膜蛋白B对结直肠癌增殖和侵袭的影响[J]. 中华胃肠外科杂志,2015(6):606-610.
4)骆洋#,秦绍岚,俞旻皓,等. 多磷酸肌醇-5-磷酸酶Ⅱ通过影响 Akt 表达调控结直肠癌增殖和侵袭[J]. 中华消化杂志,2016(1):49-52.
5)慕逸飞#,骆洋,卞正乾,俞旻皓,秦绍岚,钟鸣*. ECT2基因在结肠直肠癌组织中的表达及意义[J]. 外科理论与实践,2016,21(5):395-399.
6)秦绍岚#,俞旻皓,慕逸飞,等. 全结肠系膜切除术在右半结肠癌根治术中应用的疗效[J]. 中华胃肠外科杂志,2016,19(10):1101-1106.
7)秦绍岚#,俞旻皓,慕逸飞,祁洋,仇伊尔,骆洋,崔然,钟鸣*.全结肠系膜切除术在右半结肠癌根治术中应用的疗效[J].中华胃肠外科杂志,2016,19(10):1101-1106.
8)崔然#,周鸿,俞旻皓,等. 达芬奇机器人与腹腔镜辅助直肠癌前切除的临床疗效对照研究[J]. 外科理论与实践,2017,22(6):499-503.
9)骆洋#,秦骏,陈建军,俞旻皓,秦绍岚,仇伊尔,钟鸣*. 腹腔镜直肠癌手术中保留左结肠动脉与否疗效对比研究[J]. 中国实用外科杂志,2017,37(6):660-664.
10)骆洋#,陈建军,秦骏,俞旻皓,秦绍岚,仇伊尔,钟鸣*. 腹腔镜直肠癌根治术中肠系膜下动脉低位结扎对第3站淋巴结清扫的影响及第3站淋巴结转移危险因素分析[J]. 中华消化外科杂志,2018,17(2):154-160.
11)骆洋#,俞旻皓,陈建军,等. 腹腔镜与开腹全结直肠切除回肠储袋肛管吻合术治疗溃疡性结肠炎的临床疗效分析[J]. 中华消化外科杂志,2018,17(9):929-934.
12)骆洋,俞旻皓,陈建军,等. 腹腔镜直肠癌手术中应用中间联合头侧入路疗效分析[J]. 中国实用外科杂志,2018,38(9):1064-1067,1080.
13)仇伊尔#,骆洋,秦绍岚,崔然,秦骏,陈建军,俞旻皓,钟鸣#. 围手术期厚朴排气合剂在腹腔镜结直肠癌快速康复中疗效的随机对照研究[J]. 胃肠病学,2018,23(3):148-151.
14)崔然#,俞旻皓,钟鸣*. 肛瘘的超声与MRI检查以及3D打印模型[J].外科理论与实践,2018,23(2):178-180.
15)崔然#,俞旻皓,陈建军,等. 克罗恩病合并肛瘘的手术治疗进展[J]. 胃肠病学,2018,23(4):238-240.
16)顾磊#,刘晔,蒋春晖,俞旻皓,秦骏,徐庆*. 经肛全直肠系膜切除术结构化培训后学员学习效果的评价分析[J]. 中华结直肠疾病电子杂志,2019,8(6):631-635.
17)崔然#,俞旻皓,陈建军,等. 超声刀与单极电剪在达芬奇机器人辅助直肠癌前切除术中的疗效对照研究[J]. 中华普通外科杂志,2019,34(1):66-67.
18)李靖#,李军,吕强,王海川,钟鸣,骆洋,秦骏,俞旻皓,蔡晓燕*. 结直肠癌肿瘤组织中IncRNA-MVIH和micRNA的表达及早期诊断意义[J].中国肿瘤临床与康复,2019(5):521-524.
19)秦骏#,史苑,敬然,俞旻皓,陈建军,张斌,顾磊,蒋春晖,叶光耀,孙隆慈,Shah Jay N,钟鸣*. 外科医师非手术临床技能评分标准中导师评价的研究[J]. 中华医学教育探索杂,2019,18(10):1043-1047.
20)骆洋#,俞旻皓,陈建军,等. 脐上纵行辅助切口在腹腔镜直肠癌手术中应用的优势探讨[J]. 中华胃肠外科杂志,2020,23(3):289-293.
21)李靖#,陈建军,应隽,姜建平,骆洋,俞旻皓,钟鸣*. 加速康复外科在腹腔镜结直肠癌手术中的应用及对免疫功能的影响[J]. 腹腔镜外科杂志,2020,25(11):853-858.
22)刘赛靓#,周勇,俞旻皓,等. 右半结肠癌淋巴结清扫范围的临床研究进展[J]. 中华结直肠疾病电子杂志,2020,9(5):507-511.
23)敬然#,骆洋,秦骏,康红梅,黄轶洲,俞旻皓,钟鸣*. 吻合口支架降低结肠术后吻合口漏发生率的动物研究[J]. 中华结直肠疾病电子杂志,2020,9(6):581-585.
24)骆洋#,俞旻皓,樊钊强,等. 腹腔镜低位直肠癌术中预防性转流术的选择标准——仁济经验[J]. 腹腔镜外科杂志,2020,25(11):801-803.
25)骆洋#,俞旻皓,陈建军,等. 倒刺缝线在腹腔镜直肠癌根治术中加固吻合口的应用价值[J]. 中华消化外科杂志,2020,19(11):1205-1210.
26)钟鸣#*,骆洋,俞旻皓. 保留左结肠动脉腹腔镜直肠癌根治术的解剖基础与外科实践[J]. 中华外科杂志,2020,58(8):600-603.
27)贡婷月#,俞旻皓,钟鸣*. 初始可切除结直肠癌肝转移新辅助治疗研究进展[J]. 中华胃肠外科杂志,2021,24(3):279-282.
28)骆洋#,俞旻皓,樊钊强,等. 结直肠外科专业化程度对腹腔镜低位直肠癌术预防性造口的影响[J]. 腹腔镜外科杂志,2021,26(2):112-116.
29)史苑#,俞旻皓,钟鸣*. 英夫利西单克隆抗体治疗炎症性肠病的疗效预测标志物研究进展[J]. 中华炎性肠病杂志,2021,05(2):169-173.
30)孙凌宇#,俞旻皓,骆洋,HUANG Y Z.肠系膜下动脉根部淋巴结清扫联合血管低位或高位结扎治疗直肠癌的效果观察[J].结直肠肛门外科,2021,27(04):392-393.
31)Cong ZJ#, Hu LH#, Bian ZQ#, Ye GY, Yu MH, Gao YH, Li ZS, Yu ED*, Zhong M*. Systematic review of anastomotic leakage rate according to an international grading system following anterior resection for rectal cancer. PLoS One. 2013 Sep 25;8(9):e75519.
32)Luo Y#, Qin SL#, Yu MH, Mu YF, Wang ZS, Zhong M*. Prognostic value of regulator of G-protein signaling 6 in colorectal cancer. Biomed Pharmacother. 2015 Dec;76:147-52.
33)Luo Y#, Ye GY, Qin SL, Yu MH, Mu YF, Zhong M*. ATAD2 Overexpression Identifies Colorectal Cancer Patients with Poor Prognosis and Drives Proliferation of Cancer Cells. Gastroenterol Res Pract. 2015;2015:936564.
34)Zhang Y#, Luo Y#, Qin SL, Mu YF, Qi Y, Yu MH, Zhong M*. The clinical impact of ICOS signal in colorectal cancer patients. Oncoimmunology. 2016 Mar 10;5(5):e1141857.
35)Zhou Y#, Qiu YE#, Qin SL, Luo Y, Cui R, Qin J, Chen JJ, Yu MH, Zhong M, Shi XY*. Expression of CHD5 may serve as an independent biomarker of prognosis in colorectal cancer via immunohistochemical staining. Int J Clin Exp Pathol. 2018 May 1;11(5):2792-2798.
36)Chen J#, Luo Y#, Zhou Y#, Qin S, Qiu Y, Cui R, Yu M, Qin J, Zhong M*. Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages. Cell Physiol Biochem. 2018;46(4):1693-1703.
37)Qiu YE#, Qin J#, Luo Y, Qin SL, Mu YF, Cun R, Jiang HL, Chen JJ, Yu MH, Zhong M*. Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression. Prostaglandins Other Lipid Mediat. 2018 May;136:9-14.
38)Cao D#, Luo Y, Qin S, Yu M, Mu Y, Ye G, Yang N, Cong Z, Chen J, Qin J, Cui R, Jing R, Cao H, Zhong M*. Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway. Cell Death Dis. 2019 Sep 10;10(9):655.
39)Xu W#, Yu M, Qin J, Luo Y, Zhong M*. LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer. Cancer Manag Res. 2020 Jun 30;12:5181-5200.
40)Lyu L#, Chen D, Yu M, Yang Y#. The role of coexisting cardiovascular disease on disease severity in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2020 Nov;32(11):1480-1481.
41)Hong HJ#, Zhao X, Yu CR, Sun J, Dong F, Zang L, Lu AG, Feng B, Wang ML, Yu MH, Qiu ZJ, Qian BY, Xie L, Fingerhut A, Zheng MH*, Ma JJ*, Zhong M*. Comparative study of oncologic efficacy of cephalomedial to lateral dissection versus medial to lateral dissection in laparoscopic total mesorectal excision for rectal cancer: An RCT study. J Surg Oncol. 2021 May;123 Suppl 1:S65-S75.
发表著作：
1、《消化外科临床解剖与常用手术技巧》，林擎天、黄建平主编，上海，上海交通大学出版社，2013，ISBN 978-7-313-10090-0/R，第三篇第二十八章第三节“腹腔镜下结肠穿孔修补术”，编委
2、《精编结直肠肿瘤临床诊治》，钟鸣主编，北京，科学技术文献出版社，2020.11，ISBN 978-7-5189-7340-8，副主编
3、《现代普外疾病诊治与微创技术》，钟鸣等主编，背景，科学技术文献出版社，2020.12，ISBN 978-7-5189-7465-8，副主编
国际会议发言&壁报：
1.Speech: International College of Surgeons United States Section, 79th Annual Surgical Update, A Retrospective Controlled Clinical Study of Hand-assisted Laparoscopic and Open Colectomy in Right-side Colon Cancer, 15-17 June 2017, Seattle, Washington USA.
2.Speech: Asia Pacific Colorectal Endoscopic Summit (APCES), Pros and Cons of Left Colic Artery Preserving Technique, 13 January 2018, Shanghai, China.
3.Poster Presentation: World Congress of Gastroenterology, Increased Proton-sensing Receptor GPR4 Promotes Colorectal Cancer Progression by Activated Non-canonical Hippo Pathway, 21-24 September 2019, Istanbul, Turkey.
承担课题：
1.国家自然科学基金委员会，青年项目，81702300，转录因子TEAD1介导YAP1的促结直肠癌发展的分子机制研究，2018.1.1-2020.12.31，20万，已结题
2.上海交通大学医学院附属仁济医院临床科研培育基金，PYZY16-016，腹腔镜右半结肠癌全系膜切除术的安全性和疗效评价，2016.1.1-2018.12.31，35万，已结题
3.上海交通大学医学院附属仁济医院临床科研培育基金，PYIII20-14，腹腔镜下根治性右半结肠癌淋巴清扫范围的随机对照研究，2020.12-2022.11，10万
发明专利：
实用新型专利：
1、一种腹腔镜镜头防雾装置（CN201821346860.0），俞旻皓，钟鸣，崔然
2、腹腔镜手术助手训练装置（CN201921108447.5），钟鸣，陈建军，骆洋，崔然，秦骏，俞旻皓
3、一种用于预测大肠癌化疗效果的生物标志物、试剂盒及其应用（CN202010069465.8），洪洁，陈豪燕，张昕雨，马丹，房静远，俞旻皓
4、一种具有辅助照明装置的手术牵开器（CN202020168819.X），俞旻皓，崔然，徐一艺，钟鸣，刘泽宇
杂志编委：
International Journal on Research Case Reports and Case Series
杂志审稿人：
Scientific Reports
Cell Cycle
Journal of International Medical Research
Clinical and Experimental Pharmacology and Physiology
Pathology Research and Practice
OncoTargets and Therapy
Clinical Case Reports Journal
Cancer Biotherapy and Radiopharmaceuticals
Cancer Management and Research
Cancer Biology & Therapy
Molecular Medicine Reports
Acta Biochimica et Biophysica Sinica
《中国医学前沿杂志》

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