参与申请、完成的基金/课题项目：
1). Wnt5a信号通路在sox9基因过表达促进MSCs成软骨分化潜能中的作用与机制研究 (北京大学人民医院院内发展基金项目, #RDY2018-004) (项目主持人)；
2). Effective, stable and safe rAAV-mediated dual gene overexpression enhancing chondrogenic differentiation processes in human and minipig primary bone marrow aspirates (德国骨关节炎研究项目[Deutsche Arthrose-Hilfe e.V.])；
3). Wnt/β-catenin 信号通路在 sox9 基因介导的 hMSCs 成软骨分化中的作用及机制研究 (国家自然科学基金面上项目, #81672183) (项目第二负责人)；
4). rAAV 介导 sox9 基因诱导 hMSCs 定向软骨细胞分化复合 3D 多孔生物支架修复软骨缺损的实验研究 (国家自然科学基金应急管理项目, #81641175) (项目第二负责人)；
5). rAAV 介导 sox9 基因过表达诱导 MSCs 定向软骨细胞分化修复兔软骨缺损的实验研究 (北京大学人民医院院内发展基金项目, #RDY2016-015) (项目第二负责人)；
6). 可诱导的成纤维细胞特异性 CKLF1 基因敲除对强直性脊柱炎病理性骨化关键靶分子的影响及其作用机制的研究 (国家自然科学基金应急管理项目, #81541134) (项目第四负责人)；
7). 特异性 CKLF1 基因敲低对强直性脊柱炎髋关节囊成纤维细胞向成骨转化的影响及其作用机制的研究 (北京大学人民医院院内发展基金项目, # RDB2015-10) (项目第三负责人)；
8). 转录因子 SREBP-2 在不同能量喂食小鼠骨关节炎模型中的作用及其机制研究(国家自然科学基金应急管理项目, #81441056) (项目第四负责人)。
已发表的学术论著（包括约稿1篇和参编书籍1本）：
1). Ke Tao(陶可), Janina Frisch, Ana Rey-Rico, Jagadeesh K. Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin and Magali Cucchiarini. Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells. Stem Cell Res. Ther, 2016, 7(1):20.（影响因子4.504）
2). Ke Tao(陶可), Ana Rey-Rico, Janina Frisch, Jagadeesh K. Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin, Magali Cucchiarini. rAAV-Mediated Combined Gene Transfer and Overexpression of TGF-β and SOX9 Remodels Human Osteoarthritic Articular Cartilage. 2016 Mar 11. doi: 10.1002/jor.23228. [Epub ahead of print]. PMID: 26970525. （影响因子2.807）
3). Ke Tao(陶可), Xiao D, Weng J, Xiong A, Kang B, Zeng H. Berberine promotes bone marrow-derived mesenchymal stem cells osteogenic differentiation via canonical Wnt/β-catenin signaling pathway. Toxicol Lett, 2016 Jan 5; 240(1):68-80. （影响因子3.522）
4). Ke Tao(陶可), Tang X, Wang B, Li RJ, Zhang BQ, Lin JH, Li H. Distinct expression of chemokine-like factor 1 in synovium of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. J Huazhong Univ Sci Technolog Med Sci, 2016, 36(1):70-76. （影响因子0.834）
5). Ke Tao(陶可), Zeng H, Xiao DM, Xiong A, Weng J, Kang B. Influences of IL-6R antibody on PMMA bone cement-mediated expression of OPG and RANKL in synovial fibroblasts. J Huazhong Univ Sci Technolog Med Sci, 2014 April; 34(2):241-246. （影响因子0.779）
6). Ke Tao(陶可), H.J. Lin, H. Zeng. The role of site-1 protease in the pathogenesis of osteoarthritis. Osteoarthritis Cartilage, 2014 April; 22(Supplement):367.
国际学术大会发言(Oral Presentation)：
1). Ke Tao, et al. Different incidence of the same diet: composition and diversity of fecal microbiota may be an important risk factor for children with Kashin-Beck disease. OARSI 2020, Austria, 30th April - 8th May, 2020, Vienna, Austria.
2). Zhao Dan, Ke Tao (corresponding author), et al. Activation of Wnt signaling pathway via various molecular compound ameliorates deterioration of knee cartilage: an DMM-induced osteoarthritic animal model study. ICRS 2019, Canada, 5th-8th, Oct, 2019, Vancouver, Canada.
3). Ke Tao, et al. Dual gene transfer of fibroblast growth factor-2 and sox9 via rAAV effects on the chondrogenic and metabolic processes in human BMAs. ICRS 2019, Canada, 5th-8th, Oct, 2019, Vancouver, Canada.
4). Ke Tao, et al. Recombinant adeno associated virus mediated gene transfer and cooverexpression of transforming growth factor beta and sox9 promote the metabolic and chondrogenic activities in human bone marrow aspirates. TERMIS-EU 2017 (European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2017) 26 - 30 June, 2017, Davos, Switzerland.
Published in European Cells and Materials Vol. 33 Suppl. 2, 2017 (0198) ISSN 1473-2262.
5). Ke Tao, et al. Combined gene transfer approaches in cartilage regennerative medicine. 2016 American Orthopaedic Society of Sports Medicine (AOSSM) Fellows visit. Apr. 25, 2016. University Hospital in Homburg, Universit?t des Saarlandes, Germany.
6). Ke Tao, et al. Effects of sterol regulatory element-binding protein-2 upon the deterioration processes of chondrocytes. ICRS (i.e. International Cartilage Repair Society). Sept. 27th, 2016, Sorrento, Italy. #23.13
国际学术大会壁报展示（Posters Presentation）：
1). Ke Tao, et al. Effects of Wnt5a signaling-mediated inflammation of macrophages upon cartilage homeostasis. OARSI 2020, Austria, 30th April - 8th May, 2020, Vienna, Austria.
2). Ke Tao, et al. RUNNING EXERCISES ATTENUATES OSTEOARTHRITIS PROGRESS VIA THE INHIBITION OF CARTILAGE DEGENERATION AND FACILITATION OF SUBCHONDRAL BONE FORMATION: A DMM-INDUCED RAT KNEE OSTEOARTHRITIC MODEL. OARSI 2020, Austria, 30th April - 8th May, 2020, Vienna, Austria.
3). Ke Tao, et al. Inhibition of sterol refulatory element-binding protein-2 alleviates high-fat diet-induced deterioration of knee cartilage: an osteoarthritic animal model study. OARSI poster, May 2 - 5, 2019, Toronto, Ontario, Canada. #657
4). Liang Gao, Guisheng Xu, Ke Tao, et al. Three-dimensional Prosthesis Applicaiton and Rehabilitation for Children with Upper Limb Deficiencies. DKOU (i.e. German Congress of Orthopaedics and Traumatology) 2018 Oral presentation, Oct. 23 - 26, 2018, Berlin, Germany. #1477
5). Ke Tao, et al. Dual FGF-2 and SOX9 gene transfer via rAAV vectors: effects on the chondrogenic and metabolic processes in human bone marrow aspirates. OARSI poster, April 26 - 29, 2018, Liverpool, the United Kingdom. #560
