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指南阅读

非小细胞肺癌NCCN指南2017第7版:讨论 预后因素

发表者:张品良 人已读

Discussion 讨论

Classification and Prognostic Factors 分类及预后因素

The WHO divides lung cancer into 2 major classes based on its biology, therapy, and prognosis: NSCLC (discussed in this guideline) and small cell lung cancer (SCLC) (see the NCCN Guidelines for Small Cell Lung Cancer, available at NCCN.org). NSCLC accounts for more than 80% of all lung cancer cases, and it includes 2 major types: 1) non-squamous carcinoma (including adenocarcinoma, large-cell carcinoma, and other cell types); and 2) squamous cell (epidermoid) carcinoma. Adenocarcinoma is the most common type of lung cancer seen in the United States and is also the most frequently occurring histology in nonsmokers. In 2011, an international panel revised the classification of lung adenocarcinoma (see the Pathologic Evaluation of Lung Cancer in this Discussion), which has been adopted by the WHO. Certain prognostic factors are predictive of survival in patients with NSCLC. Good prognostic factors include early-stage disease at diagnosis, good performance status (PS) (ECOG 0, 1, or 2), no significant weight loss (not more than 5%), and female gender. 山东第一医科大学附属肿瘤医院呼吸内科张品良

基于生物学、治疗和预后,WHO将肺癌分为两个主要类型:NSCLC(在本指南讨论)和小细胞肺癌(SCLC)(见小细胞肺癌NCCN指南,可在NCCN.org获得)。非小细胞肺癌占所有肺癌病例的80%以上,包括两大类:1)非鳞癌(包括腺癌、大细胞癌和其他细胞类型的癌);和2)鳞状细胞(表皮样)癌。在美国腺癌是最常见的肺癌类型,也是非吸烟者中最常见的组织学类型。在2011年,一个国际小组修订了肺腺癌的分类(见此讨论中的肺癌病理评价),已被WHO采纳。某些预后因素可以预测非小细胞肺癌患者的生存。预后良好的因素包括诊断时早期疾病、功能状态(PS)良好(ECOG 0、1或2)、无明显的体重减轻(不超过5%)以及女性。

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本文仅供健康科普使用,不能做为诊断、治疗的依据,请谨慎参阅

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发表于:2017-07-07 10:36

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