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万鼎铭 三甲
万鼎铭 主任医师
郑大一附院 血液内科

Promegakaryoblast到底怎样翻译?

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Promegakaryoblast到底怎样翻译?

目前,在中国流行的词典:医学专业词典,英汉汉英双向科技词典,iCIBA爱词霸词典,医药大词典,有道词典,生物医药大词典及Dict.cn在线词海等Promegakaryoblast均错误翻译为----幼巨核细胞!

这是最广泛最权威的大错!从正宗原版英语Promegakaryoblast应该翻译为----前原始巨核细胞!

1. Development of platelets(血小板的发育) pluripotent stem cell(多能干细胞) → committed stem cell(定向干细胞) → CFU-GEMM (colony forming unit-granulocyte, erythrocyte, monocyte and megakaryocyte:粒细胞,红细胞,单核细胞及巨核细胞集落形成单位;多能造血祖细胞) → BFU-MK (burst forming unit-megakaryocyte:爆式巨核细胞集落形成单位;前巨核细胞系祖细胞) → CFU-MK(colony forming unit-megakaryocyte:巨核细胞集落形成单位;巨核细胞系祖细胞) → promegakaryoblast(前原始巨核细胞;前成巨核细胞) → megakaryoblast(原始巨核细胞;成巨核细胞) → promegakaryocyte(幼稚巨核细胞) → megakaryocyte(巨核细胞) → platelet(血小板)

2. Noncommitted bone marrow stem cells undergo normal cell division(细胞分裂) and sequence through several stages. The sequence of maturation is described as stage (promegakaryoblast — the proliferative compartment), stage (immature megakaryocyte or promegakarycyte) and stage (mature megakaryocyte), resulting in the CFU-MK. This committed stem cell (called a promegakaryoblast) develops into morphologically recognizable megakaryocytes.

3. The promegakaryoblast is the first morphologically recognizable megakaryocyte precursor(前体) in bone marrow, with 15 to 50 μm in diameter, large oval nuclei, and a basophilic cytoplasma lacking granules.

综上所述,Promegakaryoblast应该翻译----前原始巨核细胞!

万鼎铭
万鼎铭 主任医师
郑大一附院 血液内科