Stroke：脑动脉瘤体积并非其破裂的预测风险因子

2014-05-25 何Jason 医学专业新闻

The size of a brain aneurysm does not play a major role in its risk of bursting, a new study finds.

一项最新研究发现，脑动脉瘤的体积并非其破裂风险的主要影响因素。

A brain aneurysm occurs when a blood vessel in the brain weakens and balloons out. If it bursts, it causes a bleeding (hemorrhagic) stroke that typically results in brain damage or death.

当脑部血管结构受损和局部突出即形成动脉瘤。若脑动脉瘤破裂，可导致出血性脑卒中，可致脑部损伤或死亡。

Finnish researchers analyzed data from aneurysm patients who were followed for their entire lives, and found that about one-third of all aneurysms burst, including about one-quarter of small aneurysms.

芬兰学者通过对脑动脉瘤患者进行终身随访，证实所有脑动脉瘤中有大约三分之一破裂，其中四分之一为小动脉瘤。

The size of the aneurysm had little effect on its risk for rupture, particularly among men. Rupture risk was particularly high among women who smoked and had aneurysms that were 7 millimeters (mm) or more in diameter. The risk of rupture was exceptionally low among men who didn't smoke.

动脉瘤的大小对破裂风险的影响轻微，特别是对男性患者而言。对于吸烟的女性患者，以及直径7 mm以上的脑动脉瘤，破裂风险尤为高。非吸烟的男性脑动脉瘤患者，其破裂风险却意外地低。

"This is not to say that aneurysms in nonsmoking men never rupture, but that the risk is much lower than we previously thought. This means treating every unruptured aneurysm may be unnecessary if one is discovered in a nonsmoking man with low blood pressure," study author Dr. Seppo Juvela said in a University of Helsinki news release.

研究作者，来自赫尔辛基大学的Dr. Seppo Juvela在一份新闻稿中说：“这并不是说男性非吸烟者身上的脑动脉瘤永远不会破裂。这说明对于不吸烟且血压值较低的男性脑动脉瘤患者，并非每一例都需要处理。”

Previous short-term studies have concluded that the size of an aneurysm is the most important risk factor for rupture. This has led to small (less than 7 mm in diameter) aneurysms often being left untreated.

此前有短期研究报道，脑动脉瘤的大小是预测破裂风险最主要的因素。这导致临床医生并不治疗一些直径在7 mm以下的小动脉瘤。