To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD),
the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated.
Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower
ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in
drug-naı¨ve OCD patients. No significant correlations between ReHo value and four clinical characteristics
were found, suggesting that abnormal ReHo might be trait-related in OCD.