Dr. Michel Lucas and colleagues1 leveraged three large studies of US men and women—the Health Professionals Follow-up Study (1988–2008; n=43,599 men), the Nurses’ Health Study (1992–2008; n=73,820 women), and the NHS II (1993–2007; n=91,005 women) in which consumption of caffeine, coffee, and decaffeinated coffee was assessed every 4 years by validated food-frequency questionnaires. (Although the researchers looked at caffeine consumption from other sources such as tea, soft drinks, and chocolate, they found the major caffeine source was coffee.) In total, there were 277 deaths as a result of suicide.
In examining the pooled multivariate relative risk, Lucas et al. found that drinking caffeinated coffee actually decreased the risk of suicide. Specifically, drinking at least two to three cups (8 oz) of caffeinated coffee per day seemed to reduce the risk of suicide by about 50% as compared to those participants who consumed 1 or less cup of coffee per day. Lucas and colleagues found only small increases in benefits for drinking more than 3 cups of caffeinated coffee per day.
“Unlike previous investigations, we were able to assess association of consumption of caffeinated and non-caffeinated beverages, and we identify caffeine as the most likely candidate of any putative protective effect of coffee,” Lucas said in a press statement.2
Previous research has suggested that caffeine boosts such neurotransmitters as serotonin, dopamine, and noradrenaline in the brain, which have mild antidepressant effects. This may be the reason behind the apparent reduced suicide risk. Nonetheless, there are negative effects associated with caffeine, so the researchers cautioned patients and clinicians about large amounts of caffeine intake.
抑郁症 抑郁症病情好转，抗抑郁药自感有一定副作用，望获知能否减少药量 想获知能否尝试减少药量，因自感服药期间易困倦，头晕，
失眠焦虑抑郁症 男 19岁,失眠焦虑抑郁症,好转，希望药量减少 好转，希望药量减少
整天玩手机电脑，表情减少，语言也减少， 抑郁？？？？ 为什么
嗜睡,抑郁症 抑郁症嗜睡如何解决 如何减少睡眠时间
抑郁症 抑郁症该怎么办 如何能减少失眠
心脏病转好后运动减少是属于抑郁症吗 心脏病转好后运动减少是属于抑郁症吗 这种现象属于抑郁症的范畴吗？