【李晶】中山大学孙逸仙纪念医院 - 妇科肿瘤科 - 医生门诊时间 - 预约挂号 - 在线问诊

擅长

1.卵巢癌、宫颈癌和内膜癌手术治疗，尤其是晚期卵巢癌等疑难和复杂妇瘤的手术治疗，其中特别擅长多脏器联合切除联合腹腔热灌注化疗治疗肿瘤高负荷晚期卵巢癌、腹膜癌和腹膜播散性肉瘤。
2.擅长针对无法手术的晚期和复发患者，特别是透明细胞癌患者制定规范和系统的综合治疗方案，熟练应用化疗、靶向治疗、抗血管生成治疗和免疫治疗。

简介

博士，主任医师，教授，硕士生导师，哈佛医学院Dana Farber癌症中心访问学者；
本科毕业于中山大学中山医学院，以提前攻博形式获得中山大学妇产科学博士学位，师从我国著名妇瘤专家林仲秋教授；
国内外妇瘤指南解读和制定执笔人，每年为复发和晚期妇瘤患者，特别是透明细胞癌患者，制定规范化治疗方案。
国内妇瘤细胞减灭术联合腹腔热灌注治疗先行者，连续三年受邀参加日本妇瘤年会分享团队研究结果和经验，连续4年执笔完成中国抗癌协会妇瘤腹腔热灌注化疗指南和专家共识。
擅长卵巢癌、宫颈癌和内膜癌手术治疗，尤其是晚期卵巢癌等疑难和复杂妇瘤的手术治疗，其中特别擅长多脏器联合切除联合腹腔热灌注化疗治疗肿瘤高负荷晚期卵巢癌、腹膜癌和腹膜播散性肉瘤，是目前国内完成两种手术操作最多的医生。R0切除率达到70%，所做工作得到中国抗癌协会肯定，相关成果已成为协会指南和专家共识制定依据。

社会任职

广东省医学会妇科肿瘤学分会第一届青年委员会副主任委员。
广州抗癌协会卵巢癌专委会副主任委员。
国家限制类技术“肿瘤深部热疗和全身热疗技术培训技术培训基地”主要负责人。
中国抗癌协会唯一授权的妇科肿瘤腹腔热灌注化疗规范化应用培训基地，基地负责人。
日本肿瘤学学会国际协调员。

获奖荣誉

人民好医生；
广东省实力中青年医生；
中山大学“叶任高-李幼姬”夫妇临床医学优秀中青年教师奖；
广东省博士博士后创新人物；
强生全国青年医师手术视频比赛第一名；

科研成果

主持开展多项临床研究，发表SCI论文27篇，相关成果已被美国ASCO和亚洲指南采纳。
1. Li H, Wu M, Wu Z, Liang J, Wang L, Yang X, Lin Z, Li J: Prognostic value of preoperative soluble interleukin 2 receptor alpha as a novel immune biomarker in epithelial ovarian cancer. Cancer Immunol Immunother 2021.
2. Wu MF, Wang LJ, Ye YF, Liu CH, Lu HW, Yao TT, Zhang BZ, Chen Q, Li JB, Peng YP et al: Efficacy of neoadjuvant hyperthermic intraperitoneal chemotherapy in advanced high-grade serous ovarian cancer (the NHIPEC trial): study protocol for a randomised controlled trial. BMJ Open 2021, 11(12):e046415.
3. Liang WF, Wang LJ, Li H, Liu CH, Wu MF, Li J: The added value of CA125 normalization before interval debulking surgery to the chemotherapy response score for the prognostication of ovarian cancer patients receiving neoadjuvant chemotherapy for advanced disease. J Cancer 2021, 12(3):946-953.
4. Wang WY, Wu MF, Wu DB, Wang LJ, Li H, Lin ZQ, Li J: Calculating the dose of cisplatin that is actually utilized in hyperthermic intraperitoneal chemotherapy among ovarian cancer patients. J Ovarian Res 2021, 14(1):9.
5. Chan CY, Li H, Wu MF, Liu CH, Lu HW, Lin ZQ, Li J: A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy. Front Oncol 2021, 11:616264.
6. Liang WF, Li H, Wu JY, Liu CH, Wu MF, Li J: Identification of Ovarian Cancer Patients Most Likely to Achieve Chemotherapy Response Score 3 Following Neoadjuvant Chemotherapy: Development of a Predictive Nomogram. Front Oncol 2020, 10:560888.
7. Ma Y, Liang WF, Liu CH, Lin ZQ, Wu MF, Li J: Comparison of two types of the triple incision technique in the treatment of patients with locally advanced vulvar cancer. Int J Med Sci 2020, 17(16):2578-2584.
8. Li J, Wu M, Li H, Lin Z, Wang L: 237O Effects of neoadjuvant hyperthermic intraperitoneal chemotherapy on chemotherapy response score and recurrence for high-grade serous ovarian cancer patients with advanced disease. Annals of Oncology 2020, 31:S1336.
9. Li H, Zhang R, Chen C, Wu C, Lin H, Li J, Lin Z: Prognostic value of different metastatic sites for patients with FIGO stage IVB endometrial cancer after surgery: A SEER database analysis. J Surg Oncol 2020, 122(5):941-948.
10. Li J, Yang B, Huang K, Liu C, Dong H, Wang J, Li F, Lin Z-q: Abstract 4289: Detection of germline large genomic rearrangements in BRCA1/2 genes by a capture-based NGS panel reveals its contribution to Chinese patients with solid tumors; 2020.
11. Wu MF, Guan MM, Liu CH, Wu JY, Rao QX, Li J: The added value of fasting blood glucose to serum squamous cell carcinoma antigen for predicting oncological outcomes in cervical cancer patients receiving neoadjuvant chemotherapy followed by radical hysterectomy. Cancer Med 2019, 8(11):5068-5078.
12. Li H, Xie X, Liu Y, Huang X, Lin H, Li J, Lin Z: Comprehensive lymphadenectomy and survival prediction in uterine serous cancer patients after surgery: A population-based analysis. Eur J Surg Oncol 2020, 46(7):1339-1346.
13. Gao T, Huang XX, Wang WY, Wu MF, Lin ZQ, Li J: Feasibility and safety of neoadjuvant laparoscopic hyperthermic intraperitoneal chemotherapy in patients with advanced stage ovarian cancer: a single-center experience. Cancer Manag Res 2019, 11:6931-6940.
14. 妇科恶性肿瘤腹腔热灌注化疗临床应用专家共识(2019). 中国实用妇科与产科杂志 2019, 035(2):194-201.
15. Huang C, Lu H, Li J, Xie X, Fan L, Wang D, Tan W, Wang Y, Lin Z, Yao T: SOX2 regulates radioresistance in cervical cancer via the hedgehog signaling pathway. Gynecol Oncol 2018, 151(3):533-541.
16. Li J, Ning NY, Rao QX, Chen R, Wang LJ, Lin ZQ: Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease. BMC Cancer 2017, 17(1):517.
17. 李晶, 林仲秋: 妇科恶性肿瘤腹腔热灌注化疗临床应用专家共识. 中国实用妇科与产科杂志 2017, 9.
18. Wu MF, Li J, Lu HW, Wang LJ, Zhang BZ, Lin ZQ: Impact of the care provided by gynecologic oncologists on outcomes of cervical cancer patients treated with radical hysterectomy. Onco Targets Ther 2016, 9:1361-1370.
19. Li J, Wu MF, Lu HW, Zhang BZ, Wang LJ, Lin ZQ: Impact of Hyperglycemia on Outcomes among Patients Receiving Neoadjuvant Chemotherapy for Bulky Early Stage Cervical Cancer. PLoS One 2016, 11(11):e0166612.
20. Zheng S, Li R, Liang J, Wen Z, Huang X, Du X, Dong S, Zhu K, Chen X, Liu D et al: Serum miR-638 Combined with Squamous Cell Carcinoma-Related Antigen as Potential Screening Biomarkers for Cervical Squamous Cell Carcinoma. Genet Test Mol Biomarkers 2020, 24(4):188-194.
21. Yao T, Weng X, Yao Y, Huang C, Li J, Peng Y, Lin R, Lin Z: ALDH-1-positive cells exhibited a radioresistant phenotype that was enhanced with hypoxia in cervical cancer. BMC Cancer 2020, 20(1):891.
22. Li J, Zhou H, Wang LJ, Lu XM, Rao QX, Lu HW, Lin ZQ: A modified triple incision technique for women with locally advanced vulvar cancer: a description of the technique and outcomes. Eur J Obstet Gynecol Reprod Biol 2012, 164(2):185-190.
23. Li J, Wang LJ, Zhang BZ, Peng YP, Lin ZQ: Neoadjuvant chemotherapy with paclitaxel plus platinum for invasive cervical cancer in pregnancy: two case report and literature review. Arch Gynecol Obstet 2011, 284(3):779-783.